Thixtra

Flupentixol 0.5 mg & Melitracen 10 mg
Tablet
Description:

Maximum serum concentration is reached in about 4 hours after oral administration of Flupentixol and Melitracen. The half-life of Flupentixol is about 35 hours and that of Melitracen is about 19 hours. The combination of Flupentixol and Melitracen does not seem to influence the pharmacokinetic properties of the individual compounds.


  • Composition

    Each film coated tablet contains Flupentixol hydrochloride BP equivalent to 0.5 mg Flupentixol and Melitracen hydrochloride INN equivalent to 10 mg Melitracen.
  • Indication

    Psychogenic depression, Depressive neurosis, Psychosomatic affections accompanied by anxiety and apathy, menopausal depression, depression in alcoholics and drug-addicts.
  • Dosage & Administration

    Adults : Usually 2 tablets daily, in morning and afternoon. In severe cases, the morning dose may be increased to 2 tablets.

    Elderly patients : 1 tablet in the morning.

    Maintenance dose : Usually 1 tablet in the morning or as directed by the physician.
  • Contraindication

    It is contraindicated in the immediate recovery phase after myocardial infarction, defects in bundle-branch conduction, untreated narrow angle glaucoma and in acute alcohol, barbiturate & opioid intoxications. Not recommended for excitable patients since its activating effect may lead to exaggeration of these characteristics.
  • Precaution

    If previously the patient has been treated with tranquilizers with sedative effect these should be withdrawn gradually.
  • Side Effects

    In the recommended doses, side effects are rare. These could be transient restlessness and insomnia.
  • Drug Interaction

    This preparation may enhance the response to alcohol, barbiturates and other CNS depressants. Simultaneous administrantion of MAO-inhibitors may cause hypertensive crisis.
  • Overdose

  • Pregnancy & Lactation

    The safety of this drug has not been established in pregnancy and lactation.
  • Storage Condition

    Keep in a dry place away from light and heat. Keep out of the reach of children.
  • How Supplied

    Each box contains 30 tablets in Alu-PVDC blister pack.